Carbon Monoxide Poisoning

Carbon monoxide (CO) poisoning is a serious and potentially life-threatening medical condition that occurs when carbon monoxide, a colorless, odorless, and tasteless gas, is inhaled and binds to hemoglobin in the blood, displacing oxygen.

Causes of Carbon Monoxide Poisoning

  • Exposure to faulty or improperly maintained fuel-burning appliances, such as furnaces, water heaters, and generators
  • Running a car engine in an enclosed space, such as a garage
  • Using a charcoal grill or camp stove indoors
  • Exposure to industrial sources of carbon monoxide, such as welding or mining operations
  • Natural disasters, such as hurricanes or floods, that cause power outages and lead to the use of alternative heat sources

Symptoms of Carbon Monoxide Poisoning

  • Headache
  • Dizziness or lightheadedness
  • Nausea and vomiting
  • Confusion or disorientation
  • Weakness or fatigue
  • Chest pain or palpitations
  • Shortness of breath
  • Seizures or loss of consciousness (in severe cases)

Diagnosis of Carbon Monoxide Poisoning

Diagnosis is typically made based on a combination of clinical presentation, medical history, and laboratory tests, including:

  • Carboxyhemoglobin (COHb) level: measures the amount of carbon monoxide bound to hemoglobin in the blood
  • Pulse oximetry: measures oxygen saturation in the blood
  • Arterial blood gas (ABG): measures oxygen and carbon dioxide levels in the blood

Treatment of Carbon Monoxide Poisoning

Treatment typically involves:

  • Immediate removal from the source of exposure
  • Administration of 100% oxygen via a non-rebreather mask or endotracheal tube
  • Hyperbaric oxygen therapy (HBOT): involves breathing pure oxygen in a pressurized chamber to help reduce COHb levels and improve tissue oxygenation
  • Supportive care, such as cardiac monitoring and management of symptoms

Prevention of Carbon Monoxide Poisoning

To prevent carbon monoxide poisoning:

  • Install carbon monoxide detectors in the home, particularly near sleeping areas
  • Ensure proper maintenance and inspection of fuel-burning appliances
  • Avoid running cars or generators in enclosed spaces
  • Use charcoal grills and camp stoves outdoors only
  • Be aware of potential sources of carbon monoxide exposure, such as industrial operations or natural disasters

Complications of Carbon Monoxide Poisoning

Possible complications of carbon monoxide poisoning include:

  • Respiratory failure
  • Cardiac arrest
  • Neurological damage, such as cognitive impairment or memory loss
  • Pregnancy complications, such as miscarriage or birth defects

Prognosis of Carbon Monoxide Poisoning

The prognosis for carbon monoxide poisoning depends on the severity of exposure and promptness of treatment. In general:

  • Mild cases: full recovery is expected with minimal long-term effects
  • Severe cases: may result in permanent neurological damage, respiratory failure, or death

Article last updated on: 4th May 2025.
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