Wolff-Parkinson-White Syndrome (WPW)

Wolff-Parkinson-White syndrome (WPW) is a rare heart condition characterized by an abnormal electrical pathway in the heart. This extra pathway, known as an accessory electrical pathway, can cause the heart to beat too quickly and irregularly.

What is WPW?

WPW is a congenital condition, meaning it is present at birth. The accessory electrical pathway is usually located between the atria (upper chambers of the heart) and the ventricles (lower chambers of the heart). This extra pathway can disrupt the normal flow of electrical signals in the heart, leading to abnormal heart rhythms.

Symptoms of WPW

The symptoms of WPW can vary from person to person, but common symptoms include:

  • Palpitations (a feeling of skipped beats or irregular heartbeat)
  • Rapid heartbeat (tachycardia)
  • Shortness of breath
  • Chest pain or discomfort
  • Dizziness or lightheadedness
  • Fainting (syncope) in severe cases

Causes and Risk Factors of WPW

The exact cause of WPW is not known, but it is thought to be related to a genetic mutation. Certain factors can increase the risk of developing WPW, including:

  • Family history of WPW or other heart conditions
  • Certain congenital heart defects
  • Age (WPW is more common in children and young adults)

Diagnosis of WPW

Diagnosing WPW typically involves a combination of the following tests:

  • Electrocardiogram (ECG or EKG): measures the electrical activity of the heart
  • Holter monitor: records the heart's electrical activity over a 24-hour period
  • Event monitor: records the heart's electrical activity over a longer period, usually 30 days
  • Echocardiogram: uses sound waves to create images of the heart and its blood vessels

Treatments for WPW

Treatment for WPW depends on the severity of symptoms and the presence of any underlying heart conditions. Common treatments include:

  • Medications: such as beta blockers, anti-arrhythmic medications, or digoxin to control heart rate and rhythm
  • Catheter ablation: a minimally invasive procedure that uses radiofrequency energy to destroy the accessory electrical pathway
  • Surgical ablation: an open-heart surgery to remove the accessory electrical pathway
  • Pacemaker or implantable cardioverter-defibrillator (ICD): devices that help regulate heart rhythm and prevent life-threatening arrhythmias

Complications of WPW

If left untreated, WPW can lead to complications such as:

  • Atrial fibrillation: a type of irregular heartbeat that can increase the risk of stroke and heart failure
  • Ventricular tachycardia: a life-threatening arrhythmia that can cause cardiac arrest
  • Heart failure: a condition in which the heart is unable to pump enough blood to meet the body's needs

Prognosis and Outlook for WPW

The prognosis for WPW is generally good, especially with proper treatment. Most people with WPW can lead normal lives and participate in physical activities without restrictions. However, it is essential to work closely with a healthcare provider to manage symptoms and prevent complications.

Article last updated on: 11th April 2025.
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