Brown Recluse Spider Bites

Brown recluse spider bites are a type of venomous bite caused by the brown recluse spider (Loxosceles reclusa). These spiders are found primarily in the Midwestern and Southeastern United States, and their bites can cause significant pain, inflammation, and tissue damage.

Symptoms

  • Pain or burning at the site of the bite, which can be severe and may worsen over time
  • Redness, swelling, and blistering around the bite area
  • Necrotic lesions, or dead tissue, which can form a crater-like wound
  • Fever, chills, and headache in some cases
  • Numbness or tingling around the bite area

Causes and Risk Factors

Brown recluse spider bites occur when the spider feels threatened or cornered, and injects its venom into the skin. The venom contains a compound called sphingomyelinase D, which can cause tissue damage and necrosis. People who live in areas where brown recluse spiders are common, such as basements, attics, or woodpiles, are at higher risk of being bitten.

Diagnosis

Diagnosing a brown recluse spider bite can be challenging, as the symptoms may resemble those of other conditions. A healthcare professional will typically perform a physical examination and take a medical history to determine the cause of the symptoms. In some cases, a biopsy or laboratory tests may be ordered to confirm the diagnosis.

Treatment

Treatment for brown recluse spider bites typically involves managing the symptoms and promoting wound healing. This may include:

  • Applying ice or a cold compress to reduce pain and swelling
  • Elevating the affected area to reduce swelling
  • Using over-the-counter pain relievers, such as acetaminophen or ibuprofen
  • Applying topical antibiotics to prevent infection
  • Debridement, or surgical removal of dead tissue, in severe cases

Complications

In rare cases, brown recluse spider bites can lead to serious complications, such as:

  • Necrotic lesions that can lead to amputation
  • Infection, which can spread to other parts of the body
  • Anemia, or low red blood cell count, due to hemolysis (breakdown of red blood cells)

Prevention

To prevent brown recluse spider bites, it is recommended to:

  • Seal cracks and crevices around the home to prevent spiders from entering
  • Use insecticides or spider traps in areas where spiders are common
  • Wear protective clothing, such as long sleeves and gloves, when working in areas where spiders may be present
  • Avoid reaching or stepping into dark or undisturbed areas where spiders may be hiding

Frequently Asked Questions (FAQs)

What is a brown recluse spider bite?
A wound caused by the venom of the brown recluse spider.

Where are brown recluse spiders typically found?
Mainly in Midwestern and Southeastern United States.

What are the symptoms of a brown recluse spider bite?
Pain, redness, swelling, blistering, and potentially necrotic lesions.

How long do symptoms of a brown recluse spider bite last?
Typically several weeks to months, but can vary.

Can brown recluse spider bites be serious?
Yes, in rare cases, they can lead to severe complications.

What are the potential complications of a brown recluse spider bite?
Infection, scarring, and potentially life-threatening conditions like hemolysis or renal failure.

How are brown recluse spider bites diagnosed?
Through physical examination, medical history, and sometimes laboratory tests.

Is there an antidote for brown recluse spider venom?
No specific antidote is available, treatment is mainly supportive.

How are brown recluse spider bites treated?
With wound care, pain management, and possibly antibiotics or surgical intervention.

Can brown recluse spider bites be prevented?
Possibly, by avoiding areas where the spiders are common and wearing protective clothing.

Article last updated on: 18th October 2025.
If you have any feedback, please get in touch.

See more

 Conditions  Symptoms  Procedures

Diagnosis Pad
Medical AI Assistant with Differentials, Guidance, Transcriptions, Notes, Medical Encyclopedia and Explainable AI.
Download from App Store Download from Google Play
Available for iOS, macOS and Android.

Medical Disclaimer

The information provided is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this site. We we do not guarantee, and assume no legal liability or responsibility for the accuracy, currency, or completeness of the information provided.