Typhoid and Paratyphoid

Typhoid and paratyphoid are infectious diseases caused by the bacteria Salmonella Typhi and Salmonella Paratyphi, respectively. These diseases are commonly referred to as enteric fever.

Causes and Risk Factors

The primary cause of typhoid and paratyphoid is the ingestion of food or water contaminated with the feces of an infected person. This can occur through:

  • Consuming contaminated water or ice
  • Eating food handled by someone with the infection
  • Close contact with someone who has the infection

Symptoms

The symptoms of typhoid and paratyphoid typically develop within 6-30 days after exposure to the bacteria. Common symptoms include:

Complications

If left untreated, typhoid and paratyphoid can lead to serious complications, including:

  • Intestinal perforation, which can be life-threatening
  • Bleeding in the intestines
  • Infection of other parts of the body, such as the bones, joints, or brain
  • Septicemia, a condition where the bacteria enter the bloodstream and cause a severe infection

Diagnosis

Typhoid and paratyphoid are typically diagnosed through:

  • Blood tests to detect the presence of the bacteria or antibodies against them
  • Stool tests to detect the bacteria in the feces
  • Urine tests to detect the bacteria in the urine
  • Physical examination and medical history

Treatment

Typhoid and paratyphoid are usually treated with antibiotics, such as:

  • Ciprofloxacin
  • Azithromycin
  • Ceftriaxone

It is essential to complete the full course of antibiotic treatment, even if symptoms improve before finishing the medication.

Prevention

To prevent typhoid and paratyphoid, it is crucial to:

  • Practice good hygiene, such as washing hands frequently with soap and water
  • Avoid consuming contaminated food or water
  • Avoid close contact with someone who has the infection
  • Get vaccinated before traveling to areas where typhoid and paratyphoid are common

Vaccination

There are two types of vaccines available for typhoid:

  • Oral live attenuated vaccine (Ty21a)
  • Injectable capsular polysaccharide vaccine (Vi)

These vaccines can provide protection against typhoid, but they may not be 100% effective. It is essential to follow proper food and water precautions even after vaccination.

Conclusion

Typhoid and paratyphoid are serious infectious diseases that can be prevented with proper hygiene, safe food and water practices, and vaccination. If symptoms occur, it is crucial to seek medical attention promptly to prevent complications and ensure effective treatment.

Article last updated on: 18th June 2025.
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