Transbronchial Biopsy

A transbronchial biopsy is a medical procedure used to collect tissue samples from the lungs for examination under a microscope. The procedure involves inserting a flexible tube called a bronchoscope through the mouth or nose and into the airways, allowing the doctor to visualize the lungs and take tissue samples.

Indications

Transbronchial biopsy is typically performed to:

  • Diagnose lung diseases such as cancer, tuberculosis, or pneumonia
  • Investigate abnormal chest X-ray or CT scan findings
  • Evaluate lung function in patients with chronic respiratory conditions
  • Monitor the progression of lung disease

Procedure

The transbronchial biopsy procedure typically involves the following steps:

  1. Patient preparation: The patient is given local anesthesia and sedation to minimize discomfort during the procedure.
  2. Bronchoscope insertion: The bronchoscope is inserted through the mouth or nose and guided into the airways.
  3. Visualization: The doctor uses the bronchoscope to visualize the lungs and identify the area of interest.
  4. Tissue sampling: A special instrument called a biopsy forceps is used to collect tissue samples from the lung tissue.
  5. Sample collection: The tissue samples are collected and sent to a laboratory for examination under a microscope.

Risks and Complications

As with any medical procedure, transbronchial biopsy carries some risks and complications, including:

  • Bleeding or hemorrhage
  • Pneumothorax (collapsed lung)
  • Infection
  • Damage to the airways or lungs
  • Reaction to anesthesia or sedation

Preparation and Aftercare

To prepare for a transbronchial biopsy, patients should:

  • Fast for several hours before the procedure
  • Avoid taking certain medications that may increase bleeding risk
  • Inform their doctor about any medical conditions or allergies

After the procedure, patients should:

  • Rest for several hours to allow the anesthesia and sedation to wear off
  • Avoid strenuous activities for several days
  • Follow their doctor's instructions for managing any discomfort or pain

Results and Follow-up

The results of a transbronchial biopsy are typically available within several days to a week after the procedure. The doctor will discuss the results with the patient and provide guidance on any further treatment or follow-up care that may be necessary.

Article last updated on: 11th April 2025.
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