Thyroid Nodules

Thyroid nodules are abnormal growths of thyroid cells that form lumps or bumps within the thyroid gland. The thyroid gland is a butterfly-shaped gland located in the neck, just below the Adam's apple. It produces hormones that regulate metabolism, growth, and development.

Causes and Risk Factors

Thyroid nodules can be caused by a variety of factors, including:

  • Iodine deficiency: Lack of iodine in the diet can lead to thyroid nodules.
  • Overgrowth of thyroid tissue: Benign (non-cancerous) growths can occur in the thyroid gland, leading to nodules.
  • Cysts: Fluid-filled sacs can form within the thyroid gland, causing nodules.
  • Inflammation: Thyroiditis, or inflammation of the thyroid gland, can cause nodules to form.
  • Genetic predisposition: Family history can increase the risk of developing thyroid nodules.

Symptoms

Thyroid nodules often do not produce symptoms, but in some cases, they can cause:

  • Pain or discomfort in the neck or throat
  • Difficulty swallowing or breathing
  • Hoarseness or changes in voice
  • Coughing or wheezing
  • Neck swelling or enlargement

Diagnosis

Thyroid nodules are typically diagnosed using a combination of the following methods:

  • Physical examination: A doctor will feel the thyroid gland to check for any abnormalities.
  • Ultrasound: High-frequency sound waves are used to create images of the thyroid gland and detect nodules.
  • Thyroid function tests: Blood tests are used to measure thyroid hormone levels and assess thyroid function.
  • Biopsy: A fine-needle aspiration biopsy may be performed to collect a sample of cells from the nodule for examination under a microscope.

Treatment

Treatment for thyroid nodules depends on the size, type, and symptoms associated with the nodule. Options include:

  • Watchful waiting: Small, benign nodules may be monitored with regular check-ups and ultrasound exams.
  • Surgery: Large or cancerous nodules may require surgical removal of part or all of the thyroid gland.
  • Radiation therapy: In some cases, radiation therapy may be used to shrink or destroy cancerous nodules.
  • Medications: Thyroid hormone replacement medication may be prescribed if the nodule is affecting thyroid function.

Complications

If left untreated, thyroid nodules can lead to complications such as:

  • Cancer: A small percentage of thyroid nodules can be cancerous.
  • Thyroid dysfunction: Large or multiple nodules can affect thyroid function, leading to hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid).
  • Respiratory problems: Large nodules can compress the trachea or esophagus, causing breathing or swallowing difficulties.

Article last updated on: 6th June 2025.
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