Splenectomy

A splenectomy is a surgical procedure that involves the removal of the spleen, which is an organ located in the upper left region of the abdomen. The spleen plays a crucial role in filtering the blood and storing red blood cells, but it can be removed if it becomes damaged or diseased.

Indications for Splenectomy

The following are some of the indications for a splenectomy:

  • Trauma to the spleen, such as from a car accident or fall, which can cause rupture or severe damage
  • Splenomegaly (enlargement of the spleen) due to various conditions, including cancer, infection, or blood disorders
  • Blood diseases, such as hereditary spherocytosis, thalassemia, or sickle cell disease, which can cause the spleen to become overactive and remove too many red blood cells from the circulation
  • Cancer, including lymphoma, leukemia, or other types of cancer that affect the spleen
  • Infections, such as splenic abscess or tuberculosis, which can cause damage to the spleen
  • Portal hypertension, which is high blood pressure in the portal vein that carries blood from the intestines to the liver, and can cause the spleen to become enlarged and damaged

Types of Splenectomy

There are two main types of splenectomy:

  • Open splenectomy: This is a traditional surgical procedure that involves making a large incision in the abdomen to access and remove the spleen.
  • Laparoscopic splenectomy: This is a minimally invasive surgical procedure that involves making several small incisions in the abdomen and using a laparoscope (a thin, lighted tube with a camera) to visualize and remove the spleen.

Preoperative Preparation

Before undergoing a splenectomy, patients typically undergo the following preoperative preparation:

  • Blood tests to check for anemia, blood clotting disorders, or other conditions that may affect surgery
  • Imaging studies, such as CT scans or ultrasound, to evaluate the spleen and surrounding tissues
  • Vaccinations against certain infections, such as pneumococcus, Haemophilus influenzae type b, and meningococcus, which can be more severe in individuals without a spleen

Postoperative Care

After undergoing a splenectomy, patients typically require the following postoperative care:

  • Pain management with medication
  • Monitoring for signs of infection or bleeding
  • Follow-up appointments with their surgeon to check on the healing process and remove any sutures or staples
  • Lifetime vaccination against certain infections, as well as annual flu vaccinations
  • Avoidance of contact sports or activities that may increase the risk of injury to the abdomen

Risks and Complications

As with any surgical procedure, there are risks and complications associated with splenectomy, including:

  • Bleeding or hemorrhage
  • Infection
  • Adhesions or scar tissue formation
  • Pancreatitis (inflammation of the pancreas)
  • Diabetes (due to damage to the pancreas)
  • Increased risk of infection, particularly with encapsulated bacteria such as pneumococcus, Haemophilus influenzae type b, and meningococcus

Long-term Consequences

Individuals who have undergone a splenectomy may be at increased risk for certain long-term consequences, including:

  • Increased risk of infection, particularly with encapsulated bacteria
  • Increased risk of sepsis (a life-threatening condition that occurs when the body's response to an infection becomes uncontrolled)
  • Decreased immune function
  • Anemia or other blood disorders

Article last updated on: 6th June 2025.
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