Sinus Cancer

Sinus cancer, also known as paranasal sinus cancer, is a rare type of cancer that occurs in the sinuses, which are air-filled cavities located in the skull. The sinuses produce mucus, which helps to filter and humidify the air we breathe.

Types of Sinus Cancer

There are several types of sinus cancer, including:

  • Squamous cell carcinoma: This is the most common type of sinus cancer, accounting for about 80% of all cases. It arises from the squamous cells that line the sinuses.
  • Adenocarcinoma: This type of cancer arises from the glandular cells in the sinuses and accounts for about 10-15% of all cases.
  • Adenoid cystic carcinoma: This is a rare type of sinus cancer that arises from the salivary glands in the sinuses.
  • Melanoma: This is a rare and aggressive type of skin cancer that can occur in the sinuses.
  • Lymphoma: This is a type of cancer that affects the immune system and can occur in the sinuses.

Causes and Risk Factors

The exact cause of sinus cancer is not known, but several risk factors have been identified, including:

  • Tobacco use: Smoking or using tobacco products increases the risk of developing sinus cancer.
  • Exposure to certain chemicals: Exposure to chemicals such as wood dust, nickel, and chromium has been linked to an increased risk of sinus cancer.
  • Prior radiation therapy: People who have received radiation therapy to the head or neck area may be at increased risk of developing sinus cancer.
  • FAMILY history: A family history of cancer, particularly sinus cancer, may increase a person's risk of developing the disease.

Symptoms

The symptoms of sinus cancer can vary depending on the location and size of the tumor. Common symptoms include:

Diagnosis

Sinus cancer is typically diagnosed using a combination of the following tests:

  • Physical examination: A doctor will perform a physical examination to look for any signs of cancer, such as a lump or mass in the sinuses.
  • Imaging tests: Imaging tests such as CT scans, MRI scans, or PET scans may be used to visualize the sinuses and detect any tumors.
  • Biopsy: A biopsy involves removing a sample of tissue from the sinuses and examining it under a microscope for cancer cells.
  • Endoscopy: An endoscope is a thin, flexible tube with a camera on the end that can be inserted into the sinuses to visualize any tumors or abnormalities.

Treatment

The treatment of sinus cancer depends on the type and stage of the disease. Common treatments include:

  • Surgery: Surgery may be used to remove the tumor and any affected tissue.
  • Radiation therapy: Radiation therapy uses high-energy rays to kill cancer cells.
  • Chemotherapy: Chemotherapy uses medications to kill cancer cells.
  • Targeted therapy: Targeted therapy uses medications that specifically target cancer cells and spare healthy tissue.

Prognosis

The prognosis for sinus cancer varies depending on the type and stage of the disease. Generally, the earlier the cancer is detected and treated, the better the prognosis. The 5-year survival rate for people with sinus cancer is around 50-60%.

Article last updated on: 18th June 2025.
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