Septic Arthritis

Septic arthritis is a serious and potentially life-threatening medical condition characterized by the infection of a joint, typically caused by bacteria, but also possibly by fungi or viruses.

Causes and Risk Factors

  • Bacterial infections are the most common cause of septic arthritis, with Staphylococcus aureus being the most frequently implicated organism.
  • Other bacteria that can cause septic arthritis include Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria gonorrhoeae.
  • Fungal infections, such as Candida, can also cause septic arthritis, particularly in people with weakened immune systems.
  • Viral infections, such as hepatitis B and C, can also lead to septic arthritis.
  • Risk factors for developing septic arthritis include joint trauma or injury, previous joint surgery, prosthetic joints, compromised immune system, and underlying medical conditions such as diabetes or rheumatoid arthritis.

Symptoms

  • Sudden onset of severe joint pain and swelling, typically affecting one joint at a time.
  • Redness and warmth around the affected joint.
  • Limited range of motion in the affected joint.
  • Fever, chills, and general feeling of illness.
  • Pus or fluid accumulation in the joint.

Diagnosis

  • Physical examination to assess joint pain, swelling, and range of motion.
  • Imaging studies such as X-rays, CT scans, or MRI scans to evaluate joint damage and rule out other conditions.
  • Joint aspiration (arthrocentesis) to collect fluid from the joint for laboratory analysis.
  • Lab tests to identify the causative organism, including Gram stain, culture, and sensitivity testing.

Treatment

  • Antibiotic therapy, typically administered intravenously, to target the specific causative organism.
  • Surgical drainage of the joint to remove infected fluid and debris.
  • Immobilization of the affected joint to reduce pain and promote healing.
  • Pain management with analgesics and anti-inflammatory medications.

Complications

  • Joint destruction and permanent damage if left untreated or inadequately treated.
  • Osteoarthritis, a degenerative joint disease, as a long-term consequence of septic arthritis.
  • Bone or joint deformity.
  • Spread of infection to other joints or parts of the body (sepsis).

Prevention

  • Practice good hygiene and wound care to prevent bacterial infections.
  • Avoid sharing personal items that come into contact with bodily fluids.
  • Get vaccinated against certain bacteria, such as Haemophilus influenzae type b (Hib) and pneumococcal conjugate vaccine (PCV).

Article last updated on: 4th May 2025.
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