Sense of Smell (Lost/Changed)

The sense of smell, also known as olfaction, is a complex process that allows us to perceive and distinguish different odors. A lost or changed sense of smell can be a symptom of various underlying conditions.

Causes

  • Viral infections: Upper respiratory tract infections, such as the common cold or flu, can cause temporary loss of smell.
  • Nasal congestion: Blockage of the nasal passages due to allergies, sinusitis, or other conditions can reduce the ability to smell.
  • Head injuries: Trauma to the head can damage the olfactory nerve, leading to loss of smell.
  • Neurological disorders: Conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis can affect the sense of smell.
  • Nasal polyps: Growths in the nasal passages can obstruct airflow and reduce the ability to smell.
  • Tumors: Benign or malignant growths in the nasal cavity or brain can cause loss of smell.
  • Exposure to toxins: Prolonged exposure to certain chemicals, such as pesticides or heavy metals, can damage the olfactory system.
  • Aging: The sense of smell can decline with age, especially after the age of 60.
  • Medications: Certain medications, such as antibiotics, antihistamines, and decongestants, can affect the sense of smell.

Symptoms

  • Anosmia: Complete loss of smell.
  • Hyposmia: Reduced ability to smell.
  • Dysosmia: Distorted sense of smell, where familiar odors are perceived as unpleasant or different.
  • Phantosmia: Perception of smells that are not present in the environment.

Diagnosis

Diagnosing the cause of a lost or changed sense of smell typically involves a combination of:

  • Medical history: Reviewing the patient's medical history to identify potential underlying conditions.
  • Physical examination: Examining the nasal passages and sinuses to check for any blockages or abnormalities.
  • Smell tests: Using standardized tests, such as the University of Pennsylvania Smell Identification Test (UPSIT), to assess the patient's sense of smell.
  • Imaging studies: Using CT or MRI scans to visualize the nasal cavity and brain.

Treatment

Treatment for a lost or changed sense of smell depends on the underlying cause. Options may include:

  • Medications: Antibiotics, antihistamines, or decongestants to treat underlying infections or allergies.
  • Surgery: To remove nasal polyps or tumors.
  • Olfactory training: A type of therapy that involves repeated exposure to different odors to help improve the sense of smell.

Article last updated on: 6th June 2025.
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