Rh Factor Blood Test

The Rh factor blood test is a medical test used to determine whether an individual's blood has the Rh antigen, also known as the Rhesus factor, on the surface of their red blood cells.

Purpose of the Test

The primary purpose of the Rh factor blood test is to:

  • Determine an individual's Rh blood type (Rh positive or Rh negative)
  • Identify potential complications during pregnancy, particularly if an Rh-negative mother carries an Rh-positive fetus
  • Screen for potential transfusion reactions in patients receiving blood transfusions

How the Test is Performed

The Rh factor blood test involves a simple blood draw, typically from a vein in the arm. The blood sample is then sent to a laboratory for analysis.

Interpretation of Results

The results of the Rh factor blood test are usually reported as one of the following:

  • Rh positive (Rh+): The individual's red blood cells have the Rh antigen on their surface
  • Rh negative (Rh-): The individual's red blood cells do not have the Rh antigen on their surface

Clinical Significance

The Rh factor blood test has significant implications in:

  • Pregnancy: If an Rh-negative mother carries an Rh-positive fetus, there is a risk of hemolytic disease of the newborn (HDN), which can lead to severe anemia and other complications in the baby
  • Blood Transfusions: Receiving blood from an Rh-incompatible donor can cause a transfusion reaction, which can be life-threatening

Precautions and Considerations

In certain situations, additional precautions or considerations may be necessary:

  • Pregnant women with a history of miscarriage, abortion, or ectopic pregnancy may require Rh immunoglobulin (RhIg) to prevent sensitization
  • Individuals with a history of blood transfusions or pregnancies may require regular monitoring of their Rh status

Article last updated on: 6th June 2025.
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