Respiratory Pathogens Panel

The Respiratory Pathogens Panel is a diagnostic test used to identify the presence of various respiratory pathogens, including viruses and bacteria, that can cause respiratory infections.

What is tested?

The panel typically tests for a range of pathogens, including:

• Influenza A and B
• Respiratory Syncytial Virus (RSV)
• Adenovirus
• Human Metapneumovirus (HMPV)
• Parainfluenza viruses (PIV) 1, 2, and 3
• Coronaviruses, including SARS-CoV-2 (COVID-19)
• Bordetella pertussis (whooping cough)
• Mycoplasma pneumoniae
• Chlamydophila pneumoniae
• Legionella pneumophila

How is the test performed?

The test typically involves collecting a sample from the patient's respiratory tract, such as:

• Nasopharyngeal swab (NP swab)
• Oropharyngeal swab (OP swab)
• Sputum sample
• Tracheal aspirate

The sample is then sent to a laboratory for analysis using various techniques, including:

• Polymerase Chain Reaction (PCR)
• Reverse Transcription Polymerase Chain Reaction (RT-PCR)
• Nucleic acid amplification tests (NAATs)

What are the benefits of the test?

The Respiratory Pathogens Panel offers several benefits, including:

• Rapid diagnosis and identification of the causative pathogen
• Guidance for targeted treatment and management
• Reduced use of unnecessary antibiotics
• Improved patient outcomes and reduced morbidity

What are the limitations of the test?

The Respiratory Pathogens Panel has some limitations, including:

• False-negative results can occur if the sample is not collected properly or if the pathogen is not present in sufficient quantities
• False-positive results can occur due to contamination or cross-reactivity with other pathogens
• The test may not detect all possible respiratory pathogens

When is the test ordered?

The Respiratory Pathogens Panel is typically ordered in the following situations:

• Patients presenting with acute respiratory symptoms, such as cough, fever, and shortness of breath
• Patients with severe or complicated respiratory infections
• Immunocompromised patients or those with underlying medical conditions
• Outbreak investigations or cluster cases of respiratory illness