Rabies

Rabies is a viral disease that affects the nervous system of mammals, including humans. It is caused by the rabies virus, which is transmitted through the saliva of infected animals, usually through a bite.

What is Rabies?

Rabies is a zoonotic disease, meaning it can be transmitted from animals to humans. The virus attacks the central nervous system, causing inflammation of the brain and spinal cord. If left untreated, rabies is almost always fatal.

Symptoms of Rabies

The symptoms of rabies can vary depending on the severity of the infection and the time elapsed since the bite. The typical symptoms include:

  • Flu-like symptoms such as fever, headache, and fatigue
  • Numbness or tingling around the wound
  • Pain or itching at the site of the bite
  • Agitation, aggression, and confusion
  • Difficulty swallowing or excessive salivation
  • Paralysis or weakness in the face, arms, or legs
  • Abnormal behavior such as restlessness, anxiety, or hallucinations
  • Hydrophobia (fear of water) due to spasms in the throat and laryngeal muscles

Stages of Rabies

Rabies progresses through several stages:

  1. Incubation period: The time between the bite and the onset of symptoms, which can range from a few days to several months or even years.
  2. Prodromal stage: A period of 2-10 days during which the infected person may experience flu-like symptoms, numbness, or tingling around the wound.
  3. Neurological stage: The virus attacks the central nervous system, causing inflammation and damage to the brain and spinal cord. This stage is characterized by agitation, aggression, confusion, and difficulty swallowing.
  4. Paralytic stage: The final stage of rabies, during which the infected person may experience paralysis, coma, and eventually death.

Treatments for Rabies

If bitten or exposed to rabies, prompt medical attention is essential. The treatment options include:

  • Post-exposure prophylaxis (PEP): A series of injections with rabies immune globulin and a rabies vaccine, which can prevent the development of rabies if administered promptly after exposure.
  • Rabies vaccination: A series of injections that can provide long-term immunity against rabies. This is usually recommended for people who work with animals or travel to areas where rabies is common.
  • Wound cleaning and care: Immediate washing of the wound with soap and water, followed by application of an antiseptic, can help reduce the risk of infection.
  • Symptomatic treatment: Once symptoms appear, treatment focuses on managing the patient's condition, including pain relief, sedation, and respiratory support.

Prevention of Rabies

To prevent rabies, it is essential to:

  • Avoid contact with wild or stray animals, especially those that may be infected with rabies.
  • Vaccinate pets and domestic animals against rabies.
  • Wear protective clothing and gloves when handling animals or working in areas where rabies is common.
  • Avoid touching or handling animal carcasses or specimens that may be infected with rabies.

Article last updated on: 11th April 2025.
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