Peyronie's Disease

Peyronie's disease is a medical condition characterized by the development of fibrous scar tissue inside the penis, leading to curved, painful erections.

Causes and Risk Factors

The exact cause of Peyronie's disease is not fully understood, but it is believed to be related to:

  • Trauma or injury to the penis, which can lead to bleeding and subsequent scar tissue formation
  • Genetic predisposition
  • Aging
  • Certain medical conditions, such as Dupuytren's contracture (a condition that affects the hands)
  • Smoking

Symptoms

The symptoms of Peyronie's disease may include:

  • Curved or bent erections, which can be painful
  • Painful erections
  • Difficulty achieving or maintaining an erection
  • Shortening of the penis
  • Narrowing of the penile shaft
  • Indentation or hourglass deformity of the penile shaft

Diagnosis

Peyronie's disease is typically diagnosed through a physical examination and medical history. The doctor may also perform:

  • Ultrasound imaging to evaluate blood flow and detect any abnormalities in the penis
  • X-rays or other imaging tests to rule out other conditions that may be causing symptoms

Treatment Options

Treatment for Peyronie's disease depends on the severity of symptoms and may include:

  • Observation and monitoring, as some cases may resolve on their own
  • Medications, such as vitamin E, potassium aminobenzoate (Potaba), or collagenase, to reduce inflammation and promote healing
  • Injectable therapies, such as verapamil or interferon, to break down scar tissue
  • Surgery, such as penile plication or grafting, to correct curvature and restore function
  • Penile traction therapy, which involves using a device to stretch the penis and improve curvature

Complications

If left untreated, Peyronie's disease can lead to:

  • Chronic pain and discomfort during erections
  • Difficulty achieving or maintaining an erection
  • Reduced sexual function and satisfaction
  • Emotional distress and relationship problems

Prevention

While there is no guaranteed way to prevent Peyronie's disease, avoiding trauma or injury to the penis and maintaining good overall health may help reduce the risk of developing the condition.

Frequently Asked Questions (FAQs)

What is Peyronie's disease?
A condition characterized by the development of fibrous scar tissue inside the penis.

What are the symptoms of Peyronie's disease?
Curvature or bending of the penis, pain, and erectile dysfunction.

What causes Peyronie's disease?
The exact cause is unclear, but it may be related to injury or trauma to the penis.

How common is Peyronie's disease?
It affects approximately 1-9% of men, with varying estimates.

Can Peyronie's disease be prevented?
There is no proven way to prevent it, but avoiding penile trauma may help.

Is Peyronie's disease related to other health conditions?
It may be associated with other conditions, such as Dupuytren's contracture or erectile dysfunction.

How is Peyronie's disease diagnosed?
Through physical examination, medical history, and possibly imaging tests.

What are the treatment options for Peyronie's disease?
Oral medications, injections, surgery, and lifestyle changes may be considered.

Can Peyronie's disease be cured?
While some treatments can improve symptoms, a complete cure is not guaranteed.

Does Peyronie's disease affect fertility?
It may potentially impact fertility, but the relationship is not fully understood.

Article last updated on: 18th October 2025.
If you have any feedback, please get in touch.

See more

 Conditions  Symptoms  Procedures

Diagnosis Pad
Medical AI Assistant with Differentials, Guidance, Transcriptions, Notes, Medical Encyclopedia and Explainable AI.
Download from App Store Download from Google Play
Available for iOS, macOS and Android.

Medical Disclaimer

The information provided is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this site. We we do not guarantee, and assume no legal liability or responsibility for the accuracy, currency, or completeness of the information provided.