Peritonitis
Peritonitis is a serious and potentially life-threatening medical condition characterized by inflammation of the peritoneum, which is the thin layer of tissue that lines the abdominal cavity. The peritoneum produces fluid that helps to reduce friction between the organs in the abdomen, allowing them to move smoothly against each other.
Causes of Peritonitis
Peritonitis can be caused by a bacterial infection, which can occur due to various reasons such as:
- A rupture or perforation of an abdominal organ, such as the appendix or intestine
- A surgical wound infection
- A puncture wound to the abdomen
- An intrauterine device (IUD) or other foreign object in the abdomen
- A fungal or viral infection, although this is less common
Symptoms of Peritonitis
The symptoms of peritonitis can vary depending on the severity and location of the infection. Common symptoms include:
- Severe abdominal pain, which may be constant or come and go
- Abdominal tenderness and guarding (muscle tension)
- Nausea and vomiting
- Fever, which can be high
- Chills
- Loss of appetite
- Bloating and abdominal distension
- Diarrhea or constipation
- Rebound tenderness (pain that worsens when pressure is applied to the abdomen and then released)
Types of Peritonitis
There are several types of peritonitis, including:
- Spontaneous bacterial peritonitis (SBP): occurs in people with liver disease or cirrhosis
- Secondary peritonitis: occurs as a result of a rupture or perforation of an abdominal organ
- Tertiary peritonitis: occurs in people who are critically ill or have a compromised immune system
- Chemical peritonitis: occurs due to the presence of a chemical irritant in the abdomen, such as from a ruptured gallbladder
Diagnosis of Peritonitis
The diagnosis of peritonitis is typically made based on a combination of physical examination, medical history, and diagnostic tests, including:
- Complete blood count (CBC) to check for signs of infection or inflammation
- Blood cultures to identify the presence of bacteria in the bloodstream
- Imaging studies, such as X-rays, computed tomography (CT) scans, or ultrasound, to visualize the abdominal cavity and organs
- Paracentesis (fluid sampling) to collect fluid from the abdomen for analysis
- Laparotomy (surgical exploration of the abdomen) in some cases
Treatments for Peritonitis
The treatment of peritonitis depends on the severity and cause of the infection. Common treatments include:
- Antibiotics to treat bacterial infections
- Surgical intervention to repair or remove damaged tissue, drain abscesses, or remove foreign objects
- Fluid replacement to prevent dehydration and electrolyte imbalances
- Pain management with medications such as opioids or nonsteroidal anti-inflammatory drugs (NSAIDs)
- Nutritional support through enteral nutrition (tube feeding) or parenteral nutrition (intravenous nutrition)
- Supportive care, such as oxygen therapy and monitoring of vital signs
Complications of Peritonitis
If left untreated or inadequately treated, peritonitis can lead to serious complications, including:
- Sepsis (blood infection)
- Septic shock (life-threatening condition characterized by low blood pressure and organ dysfunction)
- Organ failure, such as kidney or liver failure
- Abscess formation (collection of pus in the abdomen)
- Adhesions (scarring) between organs or between an organ and the abdominal wall
- Intestinal obstruction or blockage
Prevention of Peritonitis
While not all cases of peritonitis can be prevented, certain measures can reduce the risk of developing the condition, including:
- Practicing good hygiene and wound care to prevent infection
- Avoiding unnecessary surgery or medical procedures
- Seeking prompt medical attention for abdominal injuries or symptoms of peritonitis
- Managing underlying medical conditions, such as liver disease or diabetes, to reduce the risk of complications
Article last updated on: 11th April 2025.
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