Peritonitis

Peritonitis is a serious and potentially life-threatening medical condition characterized by inflammation of the peritoneum, which is the thin layer of tissue that lines the abdominal cavity. The peritoneum produces fluid that helps to reduce friction between the organs in the abdomen, allowing them to move smoothly against each other.

Causes of Peritonitis

Peritonitis can be caused by a bacterial infection, which can occur due to various reasons such as:

  • A rupture or perforation of an abdominal organ, such as the appendix or intestine
  • A surgical wound infection
  • A puncture wound to the abdomen
  • An intrauterine device (IUD) or other foreign object in the abdomen
  • A fungal or viral infection, although this is less common

Symptoms of Peritonitis

The symptoms of peritonitis can vary depending on the severity and location of the infection. Common symptoms include:

Types of Peritonitis

There are several types of peritonitis, including:

  • Spontaneous bacterial peritonitis (SBP): occurs in people with liver disease or cirrhosis
  • Secondary peritonitis: occurs as a result of a rupture or perforation of an abdominal organ
  • Tertiary peritonitis: occurs in people who are critically ill or have a compromised immune system
  • Chemical peritonitis: occurs due to the presence of a chemical irritant in the abdomen, such as from a ruptured gallbladder

Diagnosis of Peritonitis

The diagnosis of peritonitis is typically made based on a combination of physical examination, medical history, and diagnostic tests, including:

  • Complete blood count (CBC) to check for signs of infection or inflammation
  • Blood cultures to identify the presence of bacteria in the bloodstream
  • Imaging studies, such as X-rays, computed tomography (CT) scans, or ultrasound, to visualize the abdominal cavity and organs
  • Paracentesis (fluid sampling) to collect fluid from the abdomen for analysis
  • Laparotomy (surgical exploration of the abdomen) in some cases

Treatments for Peritonitis

The treatment of peritonitis depends on the severity and cause of the infection. Common treatments include:

  • Antibiotics to treat bacterial infections
  • Surgical intervention to repair or remove damaged tissue, drain abscesses, or remove foreign objects
  • Fluid replacement to prevent dehydration and electrolyte imbalances
  • Pain management with medications such as opioids or nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Nutritional support through enteral nutrition (tube feeding) or parenteral nutrition (intravenous nutrition)
  • Supportive care, such as oxygen therapy and monitoring of vital signs

Complications of Peritonitis

If left untreated or inadequately treated, peritonitis can lead to serious complications, including:

Prevention of Peritonitis

While not all cases of peritonitis can be prevented, certain measures can reduce the risk of developing the condition, including:

  • Practicing good hygiene and wound care to prevent infection
  • Avoiding unnecessary surgery or medical procedures
  • Seeking prompt medical attention for abdominal injuries or symptoms of peritonitis
  • Managing underlying medical conditions, such as liver disease or diabetes, to reduce the risk of complications

Frequently Asked Questions (FAQs)

What is peritonitis?
Peritonitis is inflammation of the peritoneum, the thin layer of tissue that lines the abdominal cavity.

What causes peritonitis?
Peritonitis can be caused by a bacterial infection, often due to a rupture or perforation in the gastrointestinal tract.

What are the symptoms of peritonitis?
Symptoms may include severe abdominal pain, tenderness, fever, nausea, vomiting, and loss of appetite.

How is peritonitis diagnosed?
Diagnosis typically involves physical examination, imaging tests such as CT scans or X-rays, and laboratory tests to check for infection.

Can peritonitis be treated with antibiotics alone?
Antibiotics may be used to treat peritonitis, but in some cases, surgery may also be necessary to repair any underlying damage.

Is peritonitis a serious condition?
Peritonitis can be a life-threatening condition if left untreated or if treatment is delayed.

Can peritonitis lead to complications?
Possible complications of peritonitis include sepsis, abscesses, and adhesions in the abdominal cavity.

How long does it usually take to recover from peritonitis?
Recovery time for peritonitis can vary depending on the severity of the condition and the effectiveness of treatment.

Can peritonitis be prevented?
Some cases of peritonitis may be preventable by avoiding certain medical conditions, such as appendicitis or diverticulitis, that can increase the risk of developing peritonitis.

Is peritonitis more common in certain populations?
Peritonitis can affect anyone, but it is more commonly seen in people with certain underlying medical conditions, such as liver disease or those undergoing peritoneal dialysis.

Article last updated on: 18th October 2025.
If you have any feedback, please get in touch.

See more

 Conditions  Symptoms  Procedures

Diagnosis Pad
Medical AI Assistant with Differentials, Guidance, Transcriptions, Notes, Medical Encyclopedia and Explainable AI.
Download from App Store Download from Google Play
Available for iOS, macOS and Android.

Medical Disclaimer

The information provided is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this site. We we do not guarantee, and assume no legal liability or responsibility for the accuracy, currency, or completeness of the information provided.