Pericardial Effusion

Pericardial effusion is a medical condition characterized by the accumulation of excess fluid in the pericardial space, which is the area between the heart and the pericardium, a sac that surrounds the heart. The pericardium produces a small amount of fluid that helps to lubricate the heart and reduce friction between the heart and surrounding tissues.

Causes

Pericardial effusion can be caused by a variety of factors, including:

  • Infections, such as viral or bacterial pericarditis
  • Trauma to the chest
  • Cancer, such as lung or breast cancer that has spread to the pericardium
  • Autoimmune disorders, such as rheumatoid arthritis or lupus
  • Kidney failure
  • Heart surgery or procedures, such as coronary artery bypass grafting or pacemaker implantation

Symptoms

The symptoms of pericardial effusion can vary depending on the severity of the condition and the underlying cause. Common symptoms include:

  • Chest pain, which may be sharp or dull and can radiate to the back or arms
  • Shortness of breath
  • Fatigue
  • Palpitations or irregular heartbeat
  • Coughing or difficulty swallowing

Diagnosis

Pericardial effusion is typically diagnosed using a combination of physical examination, medical history, and diagnostic tests. These may include:

  • Chest X-ray to visualize the heart and pericardium
  • Echocardiogram to evaluate the size and function of the heart and detect any fluid accumulation in the pericardial space
  • Electrocardiogram (ECG) to assess the heart's electrical activity
  • Computed tomography (CT) scan or magnetic resonance imaging (MRI) to provide more detailed images of the heart and pericardium
  • Pericardiocentesis, which involves removing a sample of fluid from the pericardial space for analysis

Treatment

The treatment of pericardial effusion depends on the underlying cause and severity of the condition. Mild cases may be managed with:

  • Monitoring and observation
  • Pain management with medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or colchicine
  • Corticosteroids to reduce inflammation

More severe cases may require:

  • Pericardiocentesis to remove excess fluid from the pericardial space
  • Pericardial window procedure, which involves creating a small opening in the pericardium to allow for drainage of fluid
  • Surgery to repair or remove the pericardium

Complications

If left untreated, pericardial effusion can lead to serious complications, including:

  • Tamponade, which is a life-threatening condition that occurs when the excess fluid in the pericardial space compresses the heart and impairs its function
  • Cardiac arrest
  • Heart failure

Early recognition and treatment of pericardial effusion are essential to prevent these complications and improve outcomes.

Article last updated on: 6th June 2025.
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