Orf

Orf, also known as ecthyma contagiosum, is a zoonotic disease caused by the orf virus (ORFV), which belongs to the Parapoxvirus genus.

Cause and Transmission

The orf virus is primarily transmitted through direct contact with infected animals, such as sheep, goats, and cattle. The virus can enter the body through cuts or scratches on the skin, or through mucous membranes. Humans can become infected by handling infected animals, their tissues, or contaminated objects.

Symptoms

The symptoms of orf typically appear 3-7 days after exposure and may include:

Diagnosis

Diagnosis of orf is typically based on clinical presentation, medical history, and laboratory tests. Laboratory tests may include:

  • Viral culture
  • Polymerase chain reaction (PCR)
  • Serology
  • Histopathological examination of the lesion

Treatment and Management

There is no specific treatment for orf, but symptoms can be managed with:

Prevention and Control

Prevention of orf includes:

  • Avoiding contact with infected animals
  • Wearing protective clothing, including gloves and masks, when handling animals or their tissues
  • Practicing good hygiene, such as washing hands frequently
  • Vaccinating animals against the orf virus

Complications and Prognosis

Orf is typically a self-limiting disease, and most people recover within 3-6 weeks without complications. However, in rare cases, orf can lead to secondary infections, such as bacterial cellulitis or abscesses.

Epidemiology

Orf is found worldwide, but it is more common in areas where sheep and goats are raised. The disease can affect people of all ages, but it is more common among individuals who work with animals, such as farmers, veterinarians, and slaughterhouse workers.

Frequently Asked Questions (FAQs)

What is Orf?
Orf is a viral skin infection caused by a parapoxvirus.

How is Orf transmitted?
Orf is typically transmitted through direct contact with infected animals, such as sheep, goats, and cattle.

What are the symptoms of Orf?
Symptoms of Orf include a painful blister or lesion, often on the hand or finger, which may be accompanied by swelling, redness, and fever.

Is Orf contagious to others?
Orf is generally not contagious from person to person, but can be transmitted through contact with infected animals or contaminated materials.

How long does Orf last?
The duration of Orf can vary, but typically lasts around 3-6 weeks.

Can Orf be treated?
There is no specific treatment for Orf, but symptoms can be managed with supportive care, such as wound cleaning and pain relief.

Are there any complications of Orf?
Rarely, Orf can lead to secondary bacterial infections or other complications, such as lymphangitis or cellulitis.

Can Orf be prevented?
Prevention of Orf involves avoiding contact with infected animals, wearing protective clothing, and practicing good hygiene.

Who is at risk for Orf?
People who work with animals, such as farmers, veterinarians, and slaughterhouse workers, are at higher risk for contracting Orf.

Is Orf reportable?
Orf may be reportable in certain circumstances, such as outbreaks or cases involving multiple people, but this can vary depending on local health regulations.

Article last updated on: 18th October 2025.
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