Neovascular Age-Related Macular Degeneration

Neovascular age-related macular degeneration (AMD) is a type of eye disease that affects the macula, the part of the retina responsible for central vision. It is characterized by the growth of new, fragile blood vessels under the macula, which can leak fluid and cause damage to the surrounding tissue.

Causes and Risk Factors

The exact causes of neovascular AMD are not fully understood, but it is believed to be related to a combination of genetic and environmental factors. Risk factors for developing neovascular AMD include:

  • Age: Neovascular AMD is most common in people over the age of 50.
  • Family history: Having a family history of AMD increases the risk of developing the condition.
  • Smoking: Smoking has been shown to increase the risk of developing neovascular AMD.
  • High blood pressure: High blood pressure may also increase the risk of developing neovascular AMD.

Symptoms

The symptoms of neovascular AMD can vary, but common signs include:

  • Distorted vision: Straight lines may appear wavy or curved.
  • Blind spots: Blind spots or missing areas of vision may occur.
  • Loss of central vision: Neovascular AMD can cause a loss of central vision, making it difficult to perform tasks such as reading or driving.

Diagnosis

Neovascular AMD is typically diagnosed using a combination of the following tests:

  • Visual acuity test: This test measures the sharpness of vision.
  • Dilated eye exam: This exam allows the doctor to view the retina and macula in detail.
  • Fluorescein angiography: This test uses a special dye to highlight the blood vessels in the retina.
  • Optical coherence tomography (OCT): This test uses low-coherence interferometry to produce high-resolution images of the retina and macula.

Treatment

Treatment for neovascular AMD typically involves a combination of the following:

  • Anti-vascular endothelial growth factor (anti-VEGF) injections: These injections can help reduce the growth of new blood vessels and slow vision loss.
  • Laser photocoagulation: This treatment uses a laser to destroy the abnormal blood vessels.
  • Photodynamic therapy: This treatment uses a light-sensitive medication and a low-power laser to destroy the abnormal blood vessels.

Prognosis

The prognosis for neovascular AMD varies depending on the severity of the condition and the effectiveness of treatment. With prompt and proper treatment, it is possible to slow vision loss and preserve central vision. However, in some cases, neovascular AMD can lead to significant vision loss or blindness.

Frequently Asked Questions (FAQs)

What is Neovascular age-related macular degeneration?
A condition where new blood vessels grow in the eye, leading to vision loss in older adults.

What causes Neovascular age-related macular degeneration?
Exact cause unknown, but associated with aging, genetics, and environmental factors.

What are the symptoms of Neovascular age-related macular degeneration?
Blurred vision, blind spots, distorted lines, and loss of central vision.

How is Neovascular age-related macular degeneration diagnosed?
Through eye exams, including visual acuity tests, fluorescein angiography, and optical coherence tomography.

What are the treatment options for Neovascular age-related macular degeneration?
Anti-vascular endothelial growth factor injections, photodynamic therapy, and laser surgery.

Can Neovascular age-related macular degeneration be prevented?
Possibly, through lifestyle changes such as not smoking, exercising regularly, and eating a balanced diet.

Is Neovascular age-related macular degeneration hereditary?
May have a genetic component, but exact relationship unclear.

Can Neovascular age-related macular degeneration lead to blindness?
Possibly, if left untreated or poorly managed.

What is the prognosis for Neovascular age-related macular degeneration?
Variable, depending on severity and response to treatment.

Are there any ongoing research or new treatments for Neovascular age-related macular degeneration?
Yes, researchers are exploring new therapies, including gene therapy and stem cell therapy.

Article last updated on: 18th October 2025.
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