Neonatal Jaundice

Neonatal jaundice is a common condition that affects newborn babies, characterized by a yellowish discoloration of the skin and eyes due to an accumulation of bilirubin in the blood.

Causes

  • Physiological jaundice: This type of jaundice occurs in most newborns due to the breakdown of red blood cells and the liver's immaturity, which leads to a buildup of bilirubin.
  • Pathological jaundice: This type of jaundice is caused by underlying medical conditions such as hemolytic disease, infection, or congenital abnormalities of the bile ducts.
  • Breast milk jaundice: This type of jaundice occurs in breastfed babies due to substances in the mother's milk that can increase bilirubin levels.

Symptoms

  • Yellowish discoloration of the skin and eyes (sclera)
  • Lethargy or sleepiness
  • Poor feeding or weight loss
  • Dark urine or pale stools

Risk Factors

  • Preterm birth: Premature babies are more likely to develop jaundice due to their liver's immaturity.
  • Low birth weight: Babies with low birth weight are at higher risk of developing jaundice.
  • Cephalohematoma or bruising: Newborns with cephalohematoma or bruising are at increased risk of developing jaundice.
  • Family history of jaundice: Babies with a family history of jaundice are more likely to develop the condition.

Diagnosis

  • Physical examination: A healthcare provider will examine the baby's skin and eyes for signs of jaundice.
  • Bilirubin test: A blood test is used to measure the level of bilirubin in the blood.
  • Kernicterus assessment: A healthcare provider will assess the baby for signs of kernicterus, a serious complication of jaundice that can cause brain damage.

Treatment

  • Phototherapy: Exposure to special lights that help break down bilirubin in the skin.
  • Exchange transfusion: A blood transfusion that replaces the baby's blood with donor blood to reduce bilirubin levels.
  • Hydration and monitoring: Ensuring the baby is well-hydrated and closely monitoring their condition for any signs of complications.

Complications

  • Kernicterus: A serious complication that can cause brain damage, hearing loss, and developmental delays if left untreated.
  • Cerebral palsy: In severe cases of kernicterus, babies may develop cerebral palsy.
  • Hearing loss: Untreated jaundice can lead to hearing loss or impairment.

Prevention

  • Early detection and treatment: Regular check-ups with a healthcare provider can help identify jaundice early, reducing the risk of complications.
  • Adequate hydration: Ensuring the baby is well-hydrated can help reduce the risk of jaundice.
  • Breastfeeding support: Providing breastfeeding support and guidance to new mothers can help reduce the risk of breast milk jaundice.

Frequently Asked Questions (FAQs)

What is neonatal jaundice?
A condition where newborns have high levels of bilirubin, causing yellowing of skin and eyes.

What causes neonatal jaundice?
Typically due to liver immaturity, breakdown of red blood cells, or other factors affecting bilirubin processing.

How common is neonatal jaundice?
Affects around 60% of full-term newborns and up to 80% of premature infants.

What are the symptoms of neonatal jaundice?
Yellowing of skin, eyes, and mucous membranes, possibly accompanied by lethargy or poor feeding.

How is neonatal jaundice diagnosed?
Through physical examination, blood tests measuring bilirubin levels, and sometimes other diagnostic tools.

What are the risks associated with neonatal jaundice?
If left untreated, may lead to kernicterus, a rare but potentially severe brain damage condition.

How is neonatal jaundice treated?
Typically involves phototherapy, and in severe cases, blood transfusions or other interventions.

Can neonatal jaundice be prevented?
Some cases may be unavoidable, but breastfeeding support, monitoring, and early detection can help manage the condition.

What is the prognosis for newborns with neonatal jaundice?
Generally good with prompt treatment, though severe cases or those with underlying conditions may have varying outcomes.

When does neonatal jaundice typically resolve?
Usually within one to two weeks of birth, but can vary depending on individual circumstances.

Article last updated on: 18th October 2025.
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