Mitral Valve Disease

Mitral valve disease is a condition where the mitral valve, which is located between the left atrium and left ventricle of the heart, does not function properly. The mitral valve plays a crucial role in regulating blood flow through the heart, allowing blood to flow from the left atrium into the left ventricle while preventing it from flowing backward.

Types of Mitral Valve Disease

There are two main types of mitral valve disease:

  • Mitral Stenosis: This occurs when the mitral valve becomes narrowed, restricting blood flow from the left atrium into the left ventricle.
  • Mitral Regurgitation: This occurs when the mitral valve does not close properly, allowing blood to flow backward from the left ventricle into the left atrium.

Causes of Mitral Valve Disease

Mitral valve disease can be caused by a variety of factors, including:

  • Rheumatic heart disease
  • Coronary artery disease
  • Heart attack
  • Cardiomyopathy
  • Endocarditis
  • Congenital heart defects
  • Aging and wear and tear on the valve

Symptoms of Mitral Valve Disease

The symptoms of mitral valve disease can vary depending on the severity of the condition, but may include:

  • Shortness of breath
  • Fatigue
  • Chest pain or discomfort
  • Palpitations or irregular heartbeat
  • Swollen legs or feet
  • Coughing up pink, frothy mucus

Diagnosis of Mitral Valve Disease

Mitral valve disease can be diagnosed using a variety of tests, including:

  • Echocardiogram
  • Chest X-ray
  • Electrocardiogram (ECG or EKG)
  • Cardiac catheterization
  • Magnetic resonance imaging (MRI) or computed tomography (CT) scan

Treatment of Mitral Valve Disease

The treatment for mitral valve disease depends on the severity of the condition and may include:

  • Medications to manage symptoms and slow disease progression
  • Valve repair or replacement surgery
  • Minimally invasive procedures, such as balloon valvuloplasty or transcatheter mitral valve repair
  • Lifestyle modifications, such as a healthy diet and regular exercise

Complications of Mitral Valve Disease

If left untreated, mitral valve disease can lead to serious complications, including:

  • Heart failure
  • Atrial fibrillation
  • Pulmonary hypertension
  • Endocarditis
  • Stroke or transient ischemic attack (TIA)

Prognosis of Mitral Valve Disease

The prognosis for mitral valve disease varies depending on the severity of the condition and the effectiveness of treatment. With proper medical care, many people with mitral valve disease can lead active and normal lives.

Article last updated on: 6th June 2025.
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