MenACWY Vaccine

The MenACWY vaccine is a conjugate vaccine that protects against four types of meningococcal bacteria: A, C, W, and Y.

What does the vaccine do?

The MenACWY vaccine helps prevent invasive meningococcal disease (IMD), which can cause severe and potentially life-threatening infections such as:

  • Meningitis (inflammation of the lining around the brain and spinal cord)
  • Septicemia (blood infection)
  • Other serious infections

Who should get vaccinated?

The Centers for Disease Control and Prevention (CDC) recommends that the following groups receive the MenACWY vaccine:

  • All preteens and teens at 11 to 12 years old, with a booster dose at 16 years old
  • Young adults aged 18-23 years, especially those attending college or living in close quarters
  • People with certain medical conditions, such as spleen damage or immune system disorders
  • Travelers to areas where meningococcal disease is common
  • Military recruits

Administration and dosage

The MenACWY vaccine is typically administered as a single dose, with a booster dose given 5 years later for individuals who received their first dose at age 11-15. For those who receive their first dose at age 16 or older, a booster dose is not routinely recommended.

Contraindications and precautions

The MenACWY vaccine should not be given to:

  • People with a history of severe allergic reaction to any component of the vaccine or to previous doses of the vaccine
  • People with a weakened immune system, such as those with HIV/AIDS or taking immunosuppressive therapy

The vaccine should be used with caution in people with certain medical conditions, such as Guillain-Barré Syndrome.

Possible side effects

Common side effects of the MenACWY vaccine include:

  • Pain, redness, or swelling at the injection site
  • Fever
  • Headache
  • Fatigue
  • Nausea or vomiting

Vaccine effectiveness

The MenACWY vaccine is highly effective in preventing invasive meningococcal disease caused by serogroups A, C, W, and Y. Studies have shown that the vaccine can provide protection for at least 5 years.

Article last updated on: 6th June 2025.
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