Mean Platelet Volume (MPV) Blood Test

The Mean Platelet Volume (MPV) blood test is a laboratory test used to measure the average size of platelets in the blood. Platelets, also known as thrombocytes, are small, colorless cell fragments that play a crucial role in blood clotting.

What does the MPV test measure?

The MPV test measures the average volume of platelets in a sample of blood, typically expressed in femtoliters (fL). The normal range for MPV is usually between 7.5 and 11.5 fL.

Why is the MPV test performed?

The MPV test is often performed as part of a complete blood count (CBC) to help diagnose and monitor various conditions, including:

• Thrombocytopenia (low platelet count)
• Thrombocytosis (high platelet count)
• Bleeding disorders
• Platelet function disorders
• Anemia
• Infections
• Inflammatory diseases

How is the MPV test performed?

The MPV test is typically performed using an automated hematology analyzer, which measures the size and number of platelets in a blood sample. The test requires a small sample of blood, usually drawn from a vein in the arm.

Interpretation of MPV results

A high MPV result may indicate:

• Younger, larger platelets that are more reactive and prone to clotting
• Platelet activation or inflammation
• Certain bleeding disorders, such as thrombocytopenia

A low MPV result may indicate:

• Older, smaller platelets that are less reactive and less prone to clotting
• Platelet exhaustion or consumption
• Certain conditions, such as anemia or bone marrow disorders

Limitations of the MPV test

The MPV test has some limitations, including:

• Poor standardization between different laboratories and analyzers
• Limited sensitivity and specificity for certain conditions
• Potential interference from other blood components or medications