Iron Tests

Iron tests are a group of diagnostic procedures used to measure the levels of iron in the blood and diagnose iron deficiency or overload.

Types of Iron Tests

  • Serum Iron Test: Measures the amount of iron in the blood serum.
  • Total Iron-Binding Capacity (TIBC) Test: Measures the amount of proteins available for binding to iron, which helps to diagnose iron deficiency or overload.
  • Transferrin Saturation Test: Calculates the percentage of transferrin that is saturated with iron, helping to diagnose iron overload.
  • Ferritin Test: Measures the amount of ferritin in the blood, which reflects the body's stored iron levels.

Purpose of Iron Tests

Iron tests are used to:

  • Diagnose iron deficiency anemia
  • Monitor iron levels in people with chronic diseases, such as kidney disease or rheumatoid arthritis
  • Detect iron overload conditions, such as hemochromatosis
  • Monitor the effectiveness of iron supplements or other treatments for iron deficiency or overload

How Iron Tests are Performed

A healthcare provider will typically draw a blood sample from a vein in the arm using a needle and syringe. The blood sample is then sent to a laboratory for analysis.

Interpretation of Results

The results of iron tests are interpreted as follows:

  • Normal Iron Levels: Vary depending on the specific test, but generally:
    • Serum iron: 50-170 mcg/dL
    • TIBC: 240-450 mcg/dL
    • Transferrin saturation: 20-50%
    • Ferritin: 30-400 ng/mL (men), 15-200 ng/mL (women)
  • Abnormal Iron Levels: May indicate iron deficiency or overload, and may require further testing or medical evaluation.

Risks and Limitations of Iron Tests

Iron tests are generally safe and pose minimal risks. However:

  • Bleeding or bruising at the needle site
  • Infection (rare)
  • False results due to laboratory error or contamination

Special Considerations

Certain factors can affect iron test results, including:

  • Pregnancy
  • Menses
  • Recent blood transfusions
  • Certain medications (e.g., oral contraceptives, antacids)

Article last updated on: 15th June 2025.
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