Infectious Mononucleosis
Infectious mononucleosis, also known as mono or glandular fever, is a viral infection caused by the Epstein-Barr virus (EBV). It is a common illness that affects millions of people worldwide, particularly adolescents and young adults.
What is Infectious Mononucleosis?
Infectious mononucleosis is a self-limiting disease, meaning it will resolve on its own with time. The virus infects the B cells of the immune system, causing them to multiply abnormally. This leads to an overactive immune response, which results in the symptoms associated with mono.
Symptoms of Infectious Mononucleosis
The symptoms of infectious mononucleosis can vary from person to person, but common symptoms include:
- Fever
- Sore throat
- Swollen lymph nodes in the neck and armpits
- Enlarged tonsils
- White patches on the tonsils
- Extreme fatigue
- Loss of appetite
- Nausea and vomiting
- Abdominal pain
- Splenomegaly (enlargement of the spleen)
- Hepatomegaly (enlargement of the liver)
Complications of Infectious Mononucleosis
In some cases, infectious mononucleosis can lead to complications, such as:
- Splenetic rupture: a rare but potentially life-threatening condition where the spleen ruptures
- Hepatitis: inflammation of the liver
- Anemia: a decrease in red blood cells
- Thrombocytopenia: a decrease in platelets
- Neurological problems: such as meningitis, encephalitis, or Guillain-Barré syndrome
Treatments for Infectious Mononucleosis
There is no specific treatment for infectious mononucleosis, but symptoms can be managed with:
- Rest and relaxation: to help the body recover from the infection
- Pain relief medication: such as acetaminophen or ibuprofen to relieve headaches, sore throat, and fever
- Antibiotics: may be prescribed if a secondary bacterial infection develops
- Corticosteroids: may be used to reduce swelling in the throat and tonsils
- Adequate hydration: to prevent dehydration
Prevention of Infectious Mononucleosis
Infectious mononucleosis is spread through contact with saliva, mucus, and other bodily fluids. Prevention measures include:
- Avoiding close contact with people who have mono
- Not sharing food, drinks, or utensils with someone who has mono
- Practicing good hygiene: such as washing hands frequently and thoroughly
- Avoiding kissing or other intimate contact with someone who has mono
Prognosis of Infectious Mononucleosis
Most people recover from infectious mononucleosis within 2-4 weeks, but some may experience lingering fatigue and other symptoms for several months. In rare cases, the infection can lead to more serious complications, such as splenetic rupture or neurological problems.
Frequently Asked Questions (FAQs)
What is infectious mononucleosis?
Infectious mononucleosis, also known as mono or glandular fever, is a viral infection caused by the Epstein-Barr virus (EBV).
How is infectious mononucleosis transmitted?
The virus can be spread through saliva, mucus, and other bodily fluids, often through close contact with an infected person.
What are the common symptoms of infectious mononucleosis?
Symptoms may include fever, sore throat, swollen lymph nodes, fatigue, and enlarged spleen.
How long does it take for symptoms to appear after infection?
The incubation period can range from 4 to 6 weeks, but it may be longer in some cases.
Is infectious mononucleosis contagious?
Yes, people with infectious mononucleosis can be contagious for a period of time, usually before symptoms appear and for several months after.
Can infectious mononucleosis be treated with antibiotics?
No, antibiotics are not effective against viral infections like EBV, but may be prescribed to treat secondary bacterial infections.
What is the typical duration of infectious mononucleosis?
The illness usually lasts for 2-4 weeks, but fatigue and other symptoms can persist for several months.
Can infectious mononucleosis lead to complications?
Rarely, it may lead to complications such as splenic rupture, anemia, or neurological problems.
How is infectious mononucleosis diagnosed?
Diagnosis is typically made through a combination of physical examination, medical history, and laboratory tests, including blood tests and throat swab.
Is there a vaccine available for infectious mononucleosis?
Currently, there is no widely available vaccine to prevent EBV infection, but research is ongoing.
Article last updated on: 18th October 2025.
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