Homocysteine Test

The homocysteine test is a blood test used to measure the level of homocysteine in the blood. Homocysteine is an amino acid that is produced by the body as it breaks down protein. High levels of homocysteine have been linked to an increased risk of cardiovascular disease, stroke, and blood clots.

Why is the Test Performed?

The homocysteine test is performed for several reasons:

• To diagnose and monitor conditions that affect homocysteine levels, such as homocystinuria (a rare genetic disorder)
• To assess the risk of cardiovascular disease and stroke
• To evaluate the effectiveness of treatment for conditions related to high homocysteine levels
• To monitor vitamin B12, vitamin B6, and folate levels, as deficiencies in these vitamins can cause elevated homocysteine levels

How is the Test Performed?

The test involves taking a blood sample from a vein in the arm. The blood sample is then sent to a laboratory for analysis.

What are the Normal Results?

Normal results vary depending on the laboratory and the individual's age, sex, and other factors. Generally, normal homocysteine levels are:

• Less than 12 micromoles per liter (μmol/L) for adults
• Less than 10 μmol/L for children and adolescents

What do Abnormal Results Mean?

Elevated homocysteine levels may indicate:

• A deficiency in vitamin B12, vitamin B6, or folate
• Homocystinuria (a rare genetic disorder)
• Cardiovascular disease or increased risk of cardiovascular disease
• Kidney disease or kidney failure
• Certain medications, such as methotrexate and phenytoin, can also cause elevated homocysteine levels

Preparation for the Test

No special preparation is required for the test. However, it is recommended to:

• Avoid eating or drinking for at least 8 hours before the test
• Tell your doctor about any medications you are taking, as some may affect the results of the test