HIV in Pregnancy

HIV (Human Immunodeficiency Virus) infection during pregnancy is a significant concern for both the mother and the baby. If left untreated, HIV can be transmitted from mother to child during pregnancy, childbirth, or breastfeeding.

Transmission of HIV from Mother to Child

The transmission of HIV from mother to child can occur in several ways:

  • In utero: The virus can cross the placenta and infect the fetus during pregnancy.
  • During labor and delivery: The baby may be exposed to the virus in the birth canal.
  • Through breastfeeding: HIV can be transmitted through breast milk.

Risk Factors for Mother-to-Child Transmission of HIV

The risk of mother-to-child transmission of HIV is increased by several factors, including:

  • High viral load: A high level of the virus in the mother's blood increases the risk of transmission.
  • Low CD4 cell count: A weakened immune system increases the risk of transmission.
  • Prolonged labor and delivery: Longer exposure to the virus in the birth canal increases the risk of transmission.
  • Breastfeeding: HIV can be transmitted through breast milk, especially if the mother has a high viral load or is not taking antiretroviral therapy (ART).

Prevention and Treatment of Mother-to-Child Transmission of HIV

To prevent mother-to-child transmission of HIV, the following measures can be taken:

  • Antiretroviral therapy (ART): ART can reduce the viral load and prevent transmission.
  • Elective cesarean delivery: A scheduled C-section can reduce the risk of transmission during labor and delivery.
  • Avoiding breastfeeding: Formula feeding can eliminate the risk of postnatal transmission through breast milk.
  • Administering antiretroviral prophylaxis to the newborn: Giving the baby ART after birth can reduce the risk of infection.

Prenatal Care and Testing for HIV

All pregnant women should be tested for HIV as part of their prenatal care. Early diagnosis and treatment can significantly reduce the risk of mother-to-child transmission of HIV.

Management of HIV in Pregnancy

Women with HIV who become pregnant should receive comprehensive prenatal care, including:

  • Regular viral load monitoring: To assess the effectiveness of ART and adjust treatment as needed.
  • CD4 cell count monitoring: To monitor the immune system's response to treatment.
  • Ultrasound monitoring: To monitor fetal growth and development.

Conclusion

HIV in pregnancy is a significant concern, but with proper prenatal care, testing, and treatment, the risk of mother-to-child transmission can be significantly reduced. Women with HIV who become pregnant should receive comprehensive care from a multidisciplinary team of healthcare providers to ensure the best possible outcomes for both the mother and the baby.

Article last updated on: 15th June 2025.
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