Growth Hormone Tests

Growth hormone (GH) tests are used to diagnose and monitor growth hormone-related disorders, such as growth hormone deficiency or excess.

Types of Growth Hormone Tests

• Stimulation tests: These tests measure the body's ability to produce GH in response to stimulation. Examples include arginine, clonidine, and glucagon stimulation tests.
• Suppression tests: These tests measure the body's ability to suppress GH production in response to glucose ingestion. An example is the oral glucose tolerance test (OGTT).
• Insulin-like growth factor-1 (IGF-1) tests: IGF-1 is a protein produced in response to GH. Measuring IGF-1 levels can help diagnose GH-related disorders.
• Growth hormone-releasing hormone (GHRH) stimulation test: This test measures the body's response to GHRH, which stimulates GH production.

How the Tests are Performed

The tests typically involve:

• Drawing blood samples at specific times to measure GH and/or IGF-1 levels
• Administering a stimulant or suppressant, such as arginine or glucose, to assess the body's response
• Monitoring the patient's vital signs and symptoms during the test

Preparation for the Tests

Patient preparation may include:

• Fasting for a specified period before the test
• Avoiding certain medications that can interfere with GH production
• Getting a good night's sleep before the test

Interpretation of Results

The results are interpreted by a healthcare professional, taking into account the patient's medical history, symptoms, and other diagnostic tests. Abnormal results may indicate:

• Growth hormone deficiency or excess
• Pituitary gland disorders
• Hypothalamic disorders
• Other endocrine disorders

Risks and Side Effects

Risks and side effects are generally minimal, but may include:

• Pain or bruising at the injection site
• Dizziness or lightheadedness during the test
• Nausea or vomiting after glucose ingestion