Gluten Intolerance

Gluten intolerance, also known as non-celiac gluten sensitivity (NCGS), is a medical condition characterized by adverse reactions to gluten, a protein found in wheat, barley, and rye. The symptoms of gluten intolerance are similar to those of celiac disease, but the immune system does not produce the same antibodies, and the small intestine does not experience the same level of damage.

Causes and Risk Factors

The exact causes of gluten intolerance are not fully understood, but research suggests that it may be related to:

  • Genetic predisposition
  • Environmental factors, such as changes in gut bacteria
  • Imbalanced immune system response
  • Hormonal changes

Symptoms

The symptoms of gluten intolerance can vary from person to person, but common symptoms include:

Diagnosis

Diagnosing gluten intolerance can be challenging, as the symptoms are similar to those of other conditions. The following tests may be used to diagnose gluten intolerance:

  • Elimination diet: removing gluten from the diet for a period of time to see if symptoms improve
  • Reintroduction of gluten: adding gluten back into the diet to see if symptoms return
  • Blood tests: to rule out celiac disease and other conditions
  • Intestinal biopsy: to examine the small intestine for damage

Treatment

The primary treatment for gluten intolerance is a gluten-free diet. This involves:

  • Avoiding foods that contain wheat, barley, and rye
  • Reading food labels carefully to identify hidden sources of gluten
  • Seeking out gluten-free alternatives to favorite foods

Complications

If left untreated, gluten intolerance can lead to complications such as:

Prevention

While there is no sure way to prevent gluten intolerance, the following may help reduce the risk:

  • Avoiding early introduction of gluten in infants
  • Breastfeeding: which may help protect against gluten intolerance
  • Maintaining a balanced diet: rich in fruits, vegetables, and whole grains

Article last updated on: 18th June 2025.
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