Galactorrhea

Galactorrhea is a medical condition characterized by the spontaneous flow of milk from the breast, not associated with childbirth or nursing. It can occur in both men and women, although it is more common in women.

Causes

The causes of galactorrhea can be varied and include:

  • Hormonal imbalance: An excess of prolactin, a hormone produced by the pituitary gland, can cause galactorrhea. This can be due to a variety of factors, including a pituitary tumor, hypothyroidism, or certain medications.
  • Pituitary tumors: A non-cancerous tumor in the pituitary gland, called a prolactinoma, can produce excess prolactin and cause galactorrhea.
  • Thyroid disorders: Hypothyroidism (an underactive thyroid gland) can cause an increase in prolactin levels, leading to galactorrhea.
  • Certain medications: Some medications, such as antipsychotics, antidepressants, and blood pressure medications, can cause an increase in prolactin levels and lead to galactorrhea.
  • Idiopathic: In some cases, the cause of galactorrhea may be unknown.

Symptoms

The symptoms of galactorrhea can vary from person to person, but may include:

  • Spontaneous flow of milk from the breast
  • Nipple discharge that is milky or cloudy
  • Breast tenderness or swelling
  • Irregular menstrual periods in women
  • Infertility or difficulty conceiving
  • Erectile dysfunction or low libido in men

Diagnosis

The diagnosis of galactorrhea typically involves a physical examination, medical history, and laboratory tests. These may include:

  • Blood tests to check prolactin levels and thyroid function
  • Imaging studies, such as an MRI or CT scan, to rule out pituitary tumors or other abnormalities
  • A breast examination to check for any lumps or abnormalities

Treatment

The treatment of galactorrhea depends on the underlying cause and may include:

  • Medications to reduce prolactin levels, such as bromocriptine or cabergoline
  • Surgery to remove a pituitary tumor, if present
  • Thyroid hormone replacement therapy, if hypothyroidism is the cause
  • Discontinuation of any medications that may be contributing to the condition

Prognosis

The prognosis for galactorrhea varies depending on the underlying cause and the effectiveness of treatment. In general, if the underlying cause is treated successfully, the symptoms of galactorrhea can be resolved. However, in some cases, the condition may persist or recur over time.

Article last updated on: 6th June 2025.
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