Cryoablation for Cancer

Cryoablation, also known as cryotherapy or cryosurgery, is a minimally invasive procedure used to treat various types of cancer. The goal of cryoablation is to destroy cancer cells by freezing them, thereby reducing the size of the tumor and alleviating symptoms.

How it Works

Cryoablation involves the use of extremely low temperatures to freeze and kill cancer cells. A probe or needle is inserted into the tumor under imaging guidance (such as ultrasound, CT, or MRI). Liquid nitrogen or argon gas is then circulated through the probe, cooling the tip to a temperature of -40°C to -50°C. The freezing process causes ice crystals to form within the cancer cells, leading to cell death.

Types of Cancer Treated

Cryoablation can be used to treat various types of cancer, including:

  • Prostate cancer: Cryoablation is often used to treat early-stage prostate cancer or as a salvage therapy for recurrent disease.
  • Kidney cancer: Cryoablation is used to treat small renal tumors, particularly in patients who are not good candidates for surgery.
  • Liver cancer: Cryoablation can be used to treat primary liver cancer (hepatocellular carcinoma) or metastatic liver disease.
  • Breast cancer: Cryoablation is being investigated as a treatment option for early-stage breast cancer.
  • Lung cancer: Cryoablation can be used to treat small lung tumors, particularly in patients who are not good candidates for surgery.

Benefits and Advantages

Cryoablation offers several benefits and advantages over traditional surgical approaches, including:

  • Minimally invasive: Cryoablation is a relatively non-invasive procedure, resulting in less pain and faster recovery times.
  • Low risk of complications: Cryoablation has a lower risk of complications compared to traditional surgery.
  • Preservation of organ function: Cryoablation can help preserve organ function, particularly in the treatment of kidney and liver cancer.
  • Outpatient procedure: Cryoablation can often be performed on an outpatient basis, reducing hospital stay times.

Risks and Side Effects

While cryoablation is generally a safe procedure, there are potential risks and side effects to consider:

  • Pain: Patients may experience pain or discomfort during and after the procedure.
  • Bleeding: There is a risk of bleeding or hematoma formation at the treatment site.
  • Infection: As with any invasive procedure, there is a risk of infection.
  • Nerve damage: Cryoablation can cause nerve damage, particularly in the treatment of prostate cancer.

Post-Procedure Care and Follow-Up

After cryoablation, patients typically require:

  • Monitoring for complications: Patients are monitored for signs of bleeding, infection, or other complications.
  • Pain management: Patients may require pain medication to manage discomfort during the recovery period.
  • Follow-up imaging: Regular follow-up imaging is necessary to assess the effectiveness of the treatment and monitor for any signs of recurrence.

Article last updated on: 6th June 2025.
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