Anaphylaxis

Anaphylaxis is a severe, life-threatening allergic reaction that can occur within minutes of exposure to an allergen. It is a medical emergency that requires immediate attention.

What causes Anaphylaxis?

Anaphylaxis is caused by the release of chemical mediators from mast cells and basophils in response to an allergen. Common allergens that can trigger anaphylaxis include:

  • Foods: peanuts, tree nuts, fish, shellfish, milk, eggs, wheat, and soy
  • Insect stings: bee, wasp, hornet, yellow jacket, and fire ant stings
  • Medications: penicillin, cephalosporins, and other antibiotics
  • LateX

Symptoms of Anaphylaxis

The symptoms of anaphylaxis can vary from person to person, but common symptoms include:

  • Hives or itchy skin
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Abdominal cramps
  • Nausea and vomiting
  • Rapid heartbeat
  • Falling blood pressure
  • Loss of consciousness

Stages of Anaphylaxis

Anaphylaxis can progress through several stages, including:

  • Mild: symptoms are limited to the skin and mucous membranes
  • Moderate: symptoms affect multiple systems, including the respiratory and cardiovascular systems
  • Severe: symptoms are life-threatening and require immediate medical attention

Treatments for Anaphylaxis

The primary treatment for anaphylaxis is epinephrine, which is administered via an auto-injector or a syringe. Other treatments may include:

  • Antihistamines: to relieve symptoms such as hives and itching
  • Corticosteroids: to reduce inflammation
  • Bronchodilators: to help improve breathing
  • Oxygen therapy: to help increase oxygen levels in the blood
  • Intravenous fluids: to help maintain blood pressure

Emergency Response

If someone is experiencing anaphylaxis, it is essential to:

  • Call emergency services immediately
  • Administer epinephrine if available
  • Provide antihistamines and corticosteroids if prescribed by a doctor
  • Loosen tight clothing around the neck and chest
  • Keep the person calm and comfortable until medical help arrives

Prevention

To prevent anaphylaxis, it is essential to:

  • Avoid known allergens
  • Carry an epinephrine auto-injector if prescribed by a doctor
  • Wear a medical alert necklace or bracelet
  • Inform friends, family, and healthcare providers of any allergies
  • Develop an emergency action plan in case of an allergic reaction

Article last updated on: 11th April 2025.
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