Ameloblastoma

Ameloblastoma is a rare, benign (non-cancerous) tumor that occurs in the jaw, typically in the mandible (lower jawbone) or maxilla (upper jawbone). It is the most common type of odontogenic tumor, which means it arises from the tissues that form teeth.

Causes and Risk Factors

The exact cause of ameloblastoma is not known, but it is thought to arise from the epithelial cells that line the jawbone. It can occur at any age, but it is most commonly diagnosed in people between 20 and 50 years old. There is no clear link to genetics or environmental factors.

Symptoms

The symptoms of ameloblastoma may include:

  • A painless swelling or lump in the jaw
  • Loosening of teeth in the affected area
  • Pain or discomfort in the jaw or face
  • Numbness or tingling in the lower lip or chin
  • Difficulty opening the mouth or chewing

Diagnosis

Ameloblastoma is typically diagnosed using a combination of:

  • Physical examination and medical history
  • Imaging tests, such as X-rays, CT scans, or MRI scans, to visualize the tumor and surrounding bone
  • Biopsy, which involves removing a sample of tissue from the tumor for examination under a microscope

Treatment

The primary treatment for ameloblastoma is surgical removal of the tumor. The goal of surgery is to remove the entire tumor and a margin of healthy tissue around it to prevent recurrence. In some cases, additional treatments may be necessary, such as:

  • Reconstruction of the jawbone or surrounding tissues
  • Dental rehabilitation to restore chewing function and appearance
  • Radiation therapy, which is rarely used due to the benign nature of the tumor

Prognosis

The prognosis for ameloblastoma is generally good, with a high success rate for surgical treatment. However, there is a risk of recurrence, especially if the tumor is not completely removed. Regular follow-up appointments with a healthcare provider are necessary to monitor for signs of recurrence or other complications.

Complications

Possible complications of ameloblastoma include:

  • Recurrence of the tumor
  • Infection or abscess formation
  • Nerve damage, which can cause numbness or tingling in the face or mouth
  • Jaw fracture or other structural problems

Article last updated on: 6th June 2025.
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